Article
β(1)-adrenergic receptor polymorphisms and response to β-blockade in the African-American study of kidney disease and hypertension (AASK).
American journal of hypertension - 1 Jun 2011
Lee Jason, Aziz Hossein, Liu Lin, Lipkowitz Michael, O'Connor Daniel T, Richard Erin, Brophy Victoria, Wassel Christina L, Blantz Roland, Bhatnagar Vibha
Abstract excerpt
BACKGROUND: This study focuses on the relationship between β(1)-adrenergic receptor (ADRB1) polymorphisms and blood pressure response to the β-blocker metoprolol among African Americans with early hypertensive nephrosclerosis. METHODS: Participants from the African-American Study of Kidney Disease and Hypertension (AASK) trial were genotyped for ADRB1 polymorphisms: Ser49Gly and Arg389Gly. Cox proportional...
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