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Article

Relationship between beta1-adrenergic receptor polymorphisms and cardiovascular disease in patients with diabetic nephropathy.

Nephrology (Carlton, Vic.) - 1 Mar 2010

Poon Peter Yam-Kau, Szeto Cheuk-Chun, Kwan Bonnie Ching-Ha, Chow Kai-Ming, Li Philip Kam-Tao

Abstract excerpt

AIM: Activation of beta1-adrenergic receptor (beta1AR) enhances contractility and heart rate. The polymorphism Arg389Gly in the beta1AR gene was found to be functionally important in determining receptor activity. The relationship between this polymorphism and the risk of cardiovascular disease was investigated in Chinese subjects with overt diabetic nephropathy. METHODS: A total of 219 type 2 diabetic subjects...

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Identifiers

PMID: 20470286
DOI: 10.1111/j.1440-1797.2009.01182.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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