Article
β-Adrenergic receptor gene polymorphism is a genetic risk factor for cardiovascular disease: a cohort study with hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 May 2011
Iwamoto Yoshihiro, Ohishi Mitsuru, Yuan Ming, Tatara Yuji, Kato Nozomi, Takeya Yasushi, Onishi Miyuki, Maekawa Yoshihiro, Kamide Kei, Rakugi Hiromi
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) of the β-adrenergic receptor (βADR) subtypes are related to hypertension and obesity. This hospital-based cohort study with hypertensive patients evaluated five βADR SNPs in association with cardiovascular events. The cohort included 357 hypertensive patients (male = 181; mean age = 61.5 ± 11.8 years) seen between January 1998 and June 2004. The SNPs (Ser49Gly and Arg389Gly...
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