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Article

A polymorphism in the chromosome 9p21 ANRIL locus is associated to Philadelphia positive acute lymphoblastic leukemia.

Leukemia research - 1 Aug 2011

Iacobucci Ilaria, Sazzini Marco, Garagnani Paolo, Ferrari Anna, Boattini Alessio, Lonetti Annalisa, Papayannidis Cristina, Mantovani Vilma, Marasco Elena, Ottaviani Emanuela, Soverini Simona, Girelli Domenico, Luiselli Donata, Vignetti Marco, Baccarani Michele, Martinelli Giovanni

Abstract excerpt

Little is known about alterations of cyclin dependent kinase inhibitors p15INK4B, p16INK4A and of MDM2 inhibitor p14ARF due to single nucleotide polymorphisms (SNPs) located within the CDKN2A/B genes and/or neighbouring loci. In order to investigate the potential involvement of such common DNA sequence variants in leukemia susceptibility, an association study was performed by genotyping 23 SNPs spanning the MTAP,...

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Share to Chromosomes, Human, Pair 9
Share to Cyclin-Dependent Kinase Inhibitor p15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA, Neoplasm

Share to Leukemia, Myeloid, Acute

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 21414664
DOI: 10.1016/j.leukres.2011.02.020

Genes

MDM2
MTAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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