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Article

Genetic polymorphisms associated with increased risk of developing chronic myelogenous leukemia.

Oncotarget - 3 Nov 2015

Bruzzoni-Giovanelli Heriberto, González Juan R, Sigaux François, Villoutreix Bruno O, Cayuela Jean Michel, Guilhot Joëlle, Preudhomme Claude, Guilhot François, Poyet Jean-Luc, Rousselot Philippe

Abstract excerpt

Little is known about inherited factors associated with the risk of developing chronic myelogenous leukemia (CML). We used a dedicated DNA chip containing 16 561 single nucleotide polymorphisms (SNPs) covering 1 916 candidate genes to analyze 437 CML patients and 1 144 healthy control individuals. Single SNP association analysis identified 139 SNPs that passed multiple comparisons (1% false discovery rate). The...

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Topics

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Share to Cancer-related gene regulation
Share to Chronic Myeloid Leukemia Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to FGF2 gene

Share to PPARD gene

Share to Genetic Predisposition to Disease

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Lymphoma Diagnosis and Treatment

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 26474455
DOI: 10.18632/oncotarget.5915
PMCID: PMC4742176

Genes

AVEN
FGF2
GSTA3
HDAC9
IKBKB
PPARD
PSMB10
PSMB2
RIPK1
TDRKH
VAPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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