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Article

TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization.

PloS one - 11 Mar 2011

Godena Vinay K, Romano Giulia, Romano Maurizio, Appocher Chiara, Klima Raffaella, Buratti Emanuele, Baralle Francisco E, Feiguin Fabian

Abstract excerpt

TDP-43 is an evolutionarily conserved RNA binding protein recently associated with the pathogenesis of different neurological diseases. At the moment, neither its physiological role in vivo nor the mechanisms that may lead to neurodegeneration are well known. Previously, we have shown that TDP-43 mutant flies presented locomotive alterations and structural defects at the neuromuscular junctions. We have now...

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Identifiers

PMID: 21412434
DOI: 10.1371/journal.pone.0017808
PMCID: PMC3055892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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