Article
Structural and functional correlation of the human complement receptor type 1.
The Journal of investigative dermatology - 1 Jun 1990
Wong W W
Abstract excerpt
Human CR1 is widely distributed in the circulation as a surface receptor as well as in soluble form in the plasma. It mediates a variety of functions that include phagocytosis and regulation of the complement cascade. This receptor has been cloned and the primary structure reveals that the cell-bound molecule is an integral membrane protein with typical transmembrane and cytoplasmic domains. Its extracellular...
Topics
- Alleles
- Blood Cells
- Chemical Phenomena
- Chemistry
- Humans
- Polymorphism, Genetic
- Receptors, Complement
- Receptors, Complement 3b
- Sequence Homology, Nucleic Acid
- Structure-Activity Relationship
- Transcription, Genetic
