Article
The structure, genetic polymorphisms, expression and biological functions of complement receptor type 1 (CR1/CD35).
Immunopharmacology and immunotoxicology - 1 Jan 2009
Liu Dong, Niu Zhong-Xiang
Abstract excerpt
The complement system is comprised of soluble and cell surface associated proteins that recognize exogenous, altered, or potentially harmful endogenous ligands. In recent years, the complement system--particularly component C3 and its receptors--have been demonstrated to be a key link between innate and adaptive immunity. Complement receptor type 1 (CR1), the receptor for C3b/C4b complement peptides, has emerged...
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