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Article

The effect of naltrexone on alcohol's stimulant properties and self-administration behavior in social drinkers: influence of gender and genotype.

Alcoholism, clinical and experimental research - 1 Jun 2011

Setiawan Elaine, Pihl Robert O, Cox Sylvia M L, Gianoulakis Christina, Palmour Roberta M, Benkelfat Chawki, Leyton Marco

Abstract excerpt

BACKGROUND: Few pharmacological treatments for alcohol dependence are available. Moreover, the best supported treatment, naltrexone hydrochloride, appears to work for only some. METHODS: To investigate potential predictors of these differential responses, 40 social drinkers (20 women) were administered 6 days of treatment with naltrexone vs. placebo in a double-blind, counterbalanced, crossover design. At the end...

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Source

Identifiers

PMID: 21410481
DOI: 10.1111/j.1530-0277.2011.01446.x

Genes

OPRM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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