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Article

Naltrexone for the treatment of alcoholism: clinical findings, mechanisms of action, and pharmacogenetics.

CNS & neurological disorders drug targets - 1 Mar 2010

Ray Lara A, Chin Pauline F, Miotto Karen

Abstract excerpt

Naltrexone is an opioid receptor antagonist with established efficacy, albeit moderate, for the treatment of alcohol dependence. This manuscript provides a critical review of the literature on naltrexone as a pharmacotherapy for alcoholism by covering the following areas: (a) clinical findings from treatment studies; (b) pharmacokinetics and safety data; (c) medication compliance and persistence; and (d)...

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Source

Identifiers

PMID: 20201811
DOI: 10.2174/187152710790966704

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