Article
GWAS-identified colorectal cancer susceptibility loci associated with clinical outcomes.
Carcinogenesis - 1 Jul 2012
Dai Jingyao, Gu Jian, Huang Maosheng, Eng Cathy, Kopetz E Scott, Ellis Lee M, Hawk Ernest, Wu Xifeng
Abstract excerpt
Recent genome-wide association studies (GWAS) have identified several common susceptibility loci associated with the risk of colorectal cancer (CRC). However, whether these loci affect clinical outcomes of CRC is not clear. In this study, we genotyped 26 single nucleotide polymorphisms (SNPs) in 10 GWAS-identified CRC susceptibility regions and evaluated their associations with survival and recurrence in 285...
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