Article
Genetic variations in stem cell-related genes and colorectal cancer prognosis.
Journal of gastrointestinal cancer - 1 Dec 2012
Yang Hushan, Qu Falin, Myers Ronald E, Bao Guoqiang, Hyslop Terry, Hu Guang, Fei Fei, Xing Jinliang
Abstract excerpt
BACKGROUND: Many properties of cancer cells are reminiscent of those in normal stem cells. Genes important to stem cell development have been significantly implicated in the etiology and clinical outcome of colorectal cancer (CRC). However, the associations of genetic variations in these genes with CRC prognosis have not yet been elucidated. METHODS: We analyzed the effects of eight potentially functional single...
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