Article
Single nucleotide polymorphisms in the GFR-related gene and the SNP-SNP interactions on the risk of diabetic kidney disease in Chinese Han population.
Acta diabetologica - 1 Jan 2023
Liu Yanxiu, Chen Yan, Yang Qiwei, Shen Dihan, Du Zhenwu, Zhang Guizhen
Abstract excerpt
PURPOSE: Genetic susceptibility is an important pathogenic mechanism in diabetic kidney disease (DKD). However, the specific gene variant associated with DKD susceptibility remains unclear. Glomerular filtration rate (GFR), an important indicator for the process of DKD, has a heritable component. This study aimed to explore whether these GFR-related single nucleotide polymorphisms (SNPs) were associated with DKD....
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