Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.

Pharmacogenomics - 1 Jun 2005

Hung Chin-Chuan, Tai John Jen, Lin Chun-Jung, Lee Ming-Jen, Liou Horng-Huei

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate the association of the complex haplotype system of the adenosine triphosphate-binding cassette B1 (ABCB1) gene with the epilepsy treatment response. METHODS AND RESULTS: Ten polymorphisms were genotyped in 108 drug-resistant epileptic patients, 223 seizure-free patients and 287 normal controls. Highly significant linkage disequilibrium was shown among exon 12...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Epilepsy

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Taiwan

Source

Identifiers

PMID: 16004559
DOI: 10.1517/14622416.6.4.411

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.PMID 16004559Read ↗

Association of ABCB1 gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis.Semantic proximity Read ↗

The roles of variants in human multidrug resistance (MDR1) gene and their haplotypes on antiepileptic drugs response: a meta-analysis of 57 studies.Semantic proximity Read ↗

Association between ABCB1 polymorphisms and response to first-generation antiepileptic drugs in a Tunisian epileptic population.Semantic proximity Read ↗

ABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients.Semantic proximity Read ↗

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.Semantic proximity Read ↗

ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian PopulationSemantic proximity Read ↗

Polymorphism in drug transporter gene ABCB1 is associated with drug resistance in Pakistani epilepsy patients.Semantic proximity Read ↗

Polymorphisms in the Drug Transporter Gene ABCB1 Are Associated with Drug Response in Saudi Epileptic Pediatric PatientsSemantic proximity Read ↗

Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1.Semantic proximity Read ↗

Association between ABCB1 polymorphisms and response to antiepileptic drugs among Jordanian epileptic patients.Semantic proximity Read ↗

Association between G2677T/A polymorphism in ABCB1 gene and the risk of drug resistance epilepsy: An updated systematic review and meta-analysis.Semantic proximity Read ↗

ABCB1, ABCC2, SCN1A, SCN2A, GABRA1 gene polymorphisms and drug resistant epilepsy in the Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.