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Article

Association between G2677T/A polymorphism in ABCB1 gene and the risk of drug resistance epilepsy: An updated systematic review and meta-analysis.

Epilepsy research - 1 Sept 2022

Krami Al Mehdi, Ratib Chorouk, Charoute Hicham, Rouba Hassan, Roky Rachida, Barakat Abdelhamid, Nahili Halima

Abstract excerpt

PURPOSE: Epilepsy is a common serious brain condition characterized by the abnormal electrical activity of neurons. In most cases, epileptic patients respond to antiepileptic drugs. Approximately, one-third of patients prove medically intractable. The ABCB1 gene is a superfamily of ATP-binding cassette (ABC) transporters that encode a drug-transport protein, lead to cells and organs protects and eliminates toxic...

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Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 35853334
DOI: 10.1016/j.eplepsyres.2022.106977

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