Article
Association between ABCB1 polymorphisms and response to antiepileptic drugs among Jordanian epileptic patients.
Neurological research - 1 Sept 2021
Tamimi Duaa Eid, Abduljabbar Rami, Yousef Al-Motassem, Saeed Ramzi Mukred, Zawiah Mohammed
Abstract excerpt
BACKGROUND: Genetic polymorphisms of drug efflux transporters as ATP-binding cassette subfamily B, member 1 (ABCB1) have been suggested to modulate antiepileptic drugs (AEDs) response. We aimed to explore the association of ABCB1 polymorphisms and AEDs resistance among epileptic patients. METHODS: A total of 86 Jordanian epileptic patients treated with AEDs was included in the study. DNA was extracted from blood...
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