Article
Association between ABCB1 polymorphisms and response to first-generation antiepileptic drugs in a Tunisian epileptic population.
The International journal of neuroscience - 1 Aug 2018
Ajmi Marwa, Boujaafar Sana, Zouari Nadia, Amor Dorra, Nasr Asma, Rejeb Nabila Ben, Amor Sana Ben, Omezzine Asma, Benammou Sofien, Bouslama Ali
Abstract excerpt
PURPOSE: We aimed in this study to investigate the association between the ATP-Binding Cassette sub-family B, member1 (ABCB1) polymorphisms: C1236T (rs1128503), G2677T (rs2032582) and C3435T (rs1045642), and the resistance to antiepileptic drugs (AEDs). MATERIALS AND METHODS: The Polymerase Chain Reaction-Restriction Fragment Length Polymorphism genotyping of ABCB1 polymorphisms was conducted on 153 Tunisian...
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