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Article

S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation.

Circulation - 22 Mar 2011

Averill Michelle M, Barnhart Shelley, Becker Lev, Li Xin, Heinecke Jay W, Leboeuf Renee C, Hamerman Jessica A, Sorg Clemens, Kerkhoff Claus, Bornfeldt Karin E

Abstract excerpt

BACKGROUND: S100A9 is constitutively expressed in neutrophils, dendritic cells, and monocytes; is associated with acute and chronic inflammatory conditions; and is implicated in obesity and cardiovascular disease in humans. Most of the constitutively secreted S100A9 is derived from myeloid cells. A recent report demonstrated that mice deficient in S100A9 exhibit reduced atherosclerosis compared with controls and...

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Identifiers

PMID: 21382888
DOI: 10.1161/CIRCULATIONAHA.110.985523
PMCID: PMC3072335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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