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Article

S100A8 and S100A9 in human arterial wall. Implications for atherogenesis.

The Journal of biological chemistry - 16 Dec 2005

McCormick Michelle M, Rahimi Farid, Bobryshev Yuri V, Gaus Katharina, Zreiqat Hala, Cai Hong, Lord Reginald S A, Geczy Carolyn L

Abstract excerpt

Atherogenesis is a complex process involving inflammation. S100A8 and S100A9, the Ca2+-binding neutrophil cytosolic proteins, are associated with innate immunity and regulate processes leading to leukocyte adhesion and transmigration. In neutrophils and monocytes the S100A8-S100A9 complex regulates phosphorylation, NADPH-oxidase activity, and fatty acid transport. The proteins have anti-microbial properties, and...

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PMID: 16216873
DOI: 10.1074/jbc.M509442200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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