Targeting the association of calgranulin B (S100A9) with insulin resistance and type 2 diabetes.

doi:10.1007/s00109-012-0979-8

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Article

Targeting the association of calgranulin B (S100A9) with insulin resistance and type 2 diabetes.

Journal of molecular medicine (Berlin, Germany) - 1 Apr 2013

Ortega Francisco J, Mercader Josep M, Moreno-Navarrete José M, Sabater Mónica, Pueyo Neus, Valdés Sergio, Ruiz Bartomeu, Luche Elodie, Serino Matteo, Naon Deborah, Ricart Wifredo, Botas Patricia, Delgado Elias, Burcelin Remy, Frühbeck Gema, Bosch Fatima, Mingrone Gertrude, Zorzano Antonio, Fernández-Real José M

Abstract excerpt

Calgranulin B (S100A9) was recognized as a candidate type 2 diabetes (T2D) gene in the genomic profiling of muscle from a rodent model of T2D and identifying the human orthologs of genes localized in T2D susceptibility regions. Circulating and S100A9 expressions in muscle and adipose tissue, isolated fat cells, and mouse models were evaluated. A common 5'-upstream single-nucleotide polymorphism (SNP; rs3014866)...

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Identifiers

PMID: 23207880
DOI: 10.1007/s00109-012-0979-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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