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Article

Presence of SPINK-1 variant alters the course of chronic pancreatitis.

Journal of gastroenterology and hepatology - 1 Jun 2011

Sandhu Bimaljit, Vitazka Patrik, Ferreira-Gonzalez Andrea, Pandya Arti, Vachhani Ravi, Bouhaidar Doumit, Zfass Alvin, Sanyal Arun

Abstract excerpt

BACKGROUND AND AIMS: There is growing evidence that genetic mutations/variants increase susceptibility to the development and progression of chronic pancreatitis (CP). Several mutations have been identified that have a direct and indirect role in events leading to CP. Mutations in the serine protease inhibitor, Kazal type-1 (SPINK-1) gene have been reported to lower the threshold for pancreatitis in the presence...

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Identifiers

PMID: 21375584
DOI: 10.1111/j.1440-1746.2011.06713.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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