Article
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis.
Nature genetics - 1 Jun 2000
Witt H, Luck W, Hennies H C, Classen M, Kage A, Lass U, Landt O, Becker M
Abstract excerpt
Chronic pancreatitis (CP) is a continuing or relapsing inflammatory disease of the pancreas. In approximately one-third of all cases, no aetiological factor can be found, and these patients are classified as having idiopathic disease. Pathophysiologically, autodigestion and inflammation may be ca...
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