Article
Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases.
Genetic epidemiology - 1 Jul 2011
So Hon-Cheong, Gui Allen H S, Cherny Stacey S, Sham Pak C
Abstract excerpt
Recently, an increasing number of susceptibility variants have been identified for complex diseases. At the same time, the concern of "missing heritability" has also emerged. There is however no unified way to assess the heritability explained by individual genetic variants for binary outcomes. A systemic and quantitative assessment of the degree of "missing heritability" for complex diseases is lacking. In this...
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