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Article

The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene.

British journal of clinical pharmacology - 1 Oct 2011

McGettigan Patricia, Lincz Lisa F, Attia John, McElduff Patrick, Bissett Linda, Peel Roseanne, Stokes Barrie, Hancock Stephen, Henderson Kim, Seldon Michael, Henry David

Abstract excerpt

AIMS: To investigate whether polymorphisms of the cyclo-oxygenase-2 (COX-2) gene modify the adverse cardiovascular effects of COX-2 inhibitors. METHODS: A case control study was conducted in the Hunter Region of New South Wales, Australia. Cases (n= 460) were hospitalized with acute coronary syndrome (ACS). Controls (n= 640) were recruited from the electoral rolls. Structured interviews gathered information on...

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Identifiers

PMID: 21371074
DOI: 10.1111/j.1365-2125.2011.03957.x
PMCID: PMC3195745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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