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Article

Genetic polymorphisms and the cardiovascular risk of non-steroidal anti-inflammatory drugs.

The American journal of cardiology - 15 Jun 2010

St Germaine Christine G, Bogaty Peter, Boyer Luce, Hanley James, Engert James C, Brophy James M

Abstract excerpt

The cardiovascular safety of cyclooxygenase-2-selective (coxibs) and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) is of concern, although most users remain free of adverse outcomes. A gene-drug interaction could modulate this cardiovascular risk through prostaglandin synthesis or in...

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Source

Identifiers

PMID: 20538124
DOI: 10.1016/j.amjcard.2010.01.352

Genes

CRP
PTGS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20538124-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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