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Article

Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk.

Breast cancer research : BCR - 1 Jan 2006

Shen Jing, Gammon Marilie D, Terry Mary Beth, Teitelbaum Susan L, Neugut Alfred I, Santella Regina M

Abstract excerpt

INTRODUCTION: The association between use of nonsteroidal anti-inflammatory drugs (NSAIDs) and breast cancer risk remains unclear. Inconsistencies in previously reported findings may be partly due to differences in expression of cyclooxygenase (COX)-2. We hypothesized that genetic polymorphisms (COX-2 .926, COX-2 .5209, and COX-2 .8473) may reduce overall breast cancer risk or risk for subtypes of breast cancer...

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Source

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Identifiers

PMID: 17181859
DOI: 10.1186/bcr1629
PMCID: PMC1797023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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