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Article

TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy.

Allergy - 1 Aug 2011

Liu J, Rädler D, Illi S, Klucker E, Turan E, von Mutius E, Kabesch M, Schaub B

Abstract excerpt

BACKGROUND: Toll-like receptor (TLR) polymorphisms have been associated with atopic diseases in children and adults. Development of atopic diseases may be modified by TLR-mediated signals that modulate T-regulatory cells (Tregs) early in life when maternal influences are still present and relevant. The aim of this study was to assess whether genetic TLR variants influence Tregs in neonates. METHODS: Twelve single...

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Source

Identifiers

PMID: 21371045
DOI: 10.1111/j.1398-9995.2011.02573.x

Genes

TLR2
FOXP3
TLR1
TLR10
LAG3
TNF
TLR4
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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