Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy Pathogenesis

Abstract excerpt

Reduced early microbial exposure in early life has become a leading candidate to explain the escalating rate of allergic disease and has generated intense interest in the interaction between the developing immune system and the microbial environment. Infants depend on "signals" from the microbial environment to mature both T-helper cell type 1 and regulatory immune function. These signals, mediated through...

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