Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of TH17 markers early in life through maternal farm exposure.

The Journal of allergy and clinical immunology - 1 Mar 2014

Lluis Anna, Ballenberger Nikolaus, Illi Sabina, Schieck Maximilian, Kabesch Michael, Illig Thomas, Schleich Isolde, von Mutius Erika, Schaub Bianca

Abstract excerpt

BACKGROUND: Previous studies suggested that maternal farm exposure during pregnancy modulates early immune development toward an allergy-protective status potentially mediated by TH1 or regulatory T (Treg) cells. However, the underlying mechanisms might involve immune modulation of additional T-cell populations, such as TH17 cells, influenced by genetic predisposition. OBJECTIVE: We examined the role of maternal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Domestic
Share to Environmental Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fetal Blood

Share to Forkhead Transcription Factors

Share to Hypersensitivity

Share to Maternal Exposure

Share to T-Lymphocytes, Regulatory

Share to Th17 Cells

Source

Identifiers

PMID: 24275363
DOI: 10.1016/j.jaci.2013.09.030

Genes

FOXP3
RORC
LAG3
RORA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of TH17 markers early in life through maternal farm exposure.PMID 24275363Read ↗

Prenatal and Perinatal Environmental Influences Shaping the Neonatal Immune System: A Focus on Asthma and Allergy OriginsSemantic proximity Read ↗

Maternal allergic disease history affects childhood allergy development through impairment of neonatal regulatory T-cells.Semantic proximity Read ↗

Putative regulatory T cells are impaired in cord blood from neonates with hereditary allergy risk.Semantic proximity Read ↗

TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy.Semantic proximity Read ↗

In-utero exposures and the evolving epidemiology of paediatric allergySemantic proximity Read ↗

Childhood Immune Maturation and Allergy Development: Regulation by Maternal Immunity and Microbial ExposureSemantic proximity Read ↗

A switch in regulatory T cells through farm exposure during immune maturation in childhood.Semantic proximity Read ↗

Environmental exposures during pregnancy: Mechanistic effects on immunitySemantic proximity Read ↗

Does allergy begin in utero?Semantic proximity Read ↗

Prenatal and early-life exposures alter expression of innate immunity genes: the PASTURE cohort study.Semantic proximity Read ↗

Immune Responsiveness to LPS Determines Risk of Childhood Wheeze and Asthma in 17q21 Risk Allele Carriers.Semantic proximity Read ↗

The Foetal Origins of Allergy and Potential Nutritional Interventions to Prevent DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.