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Article

Maternal allergic disease history affects childhood allergy development through impairment of neonatal regulatory T-cells.

Respiratory research - 20 Sept 2016

Meng Shan-Shan, Gao Rong, Yan Bing-di, Ren Jin, Wu Fei, Chen Peng, Zhang Jie, Wang Li-Fang, Xiao Yuan-Ming, Liu Jing

Abstract excerpt

BACKGROUND: Maternal allergic disease history and impaired regulatory T-cells (Tregs) are critical risk factors for allergy development in children. However, the mechanisms that underlie these risk factors remain poorly defined. Therefore, the aim of this study was to assess whether maternal allergies affect the Tregs of offspring and lead to allergy development in childhood. METHODS: A total of 332 mothers of...

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Source

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Identifiers

PMID: 27646403
DOI: 10.1186/s12931-016-0430-8
PMCID: PMC5028930

Genes

FOXP3
LPA
TLR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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