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Article

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.

The Pediatric infectious disease journal - 1 May 2014

Koponen Petri, Vuononvirta Juho, Nuolivirta Kirsi, Helminen Merja, He Qiushui, Korppi Matti

Abstract excerpt

BACKGROUND: Toll-like receptors (TLRs) are a pivotal part of the innate immunity system. Variations in TLR genes have been connected to autoimmune conditions, such as allergy and asthma. The TLR2 subfamily comprises TLR1, TLR2, TLR6 and TLR 10. We hypothesized that polymorphism of the TLR2 subfamily may be associated with prevalence of post-bronchiolitic asthma and/or atopy. METHODS: TLR1rs5743618, TLR2rs5743708...

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Topics

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Share to Asthma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24445834
DOI: 10.1097/INF.0000000000000253

Genes

TLR1
TLR2
TLR6

Provenance

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Related research

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The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.PMID 24445834Read ↗

Polymorphism in the gene encoding toll-like receptor 10 may be associated with asthma after bronchiolitis.Semantic proximity Read ↗

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IL-10 gene polymorphism is associated with preschool atopy and early-life recurrent wheezing after bronchiolitis in infancy.Semantic proximity Read ↗

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