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Article

Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach.

PloS one - 22 Feb 2011

Edwards Yvonne J K, Beecham Gary W, Scott William K, Khuri Sawsan, Bademci Guney, Tekin Demet, Martin Eden R, Jiang Zhijie, Mash Deborah C, ffrench-Mullen Jarlath, Pericak-Vance Margaret A, Tsinoremas Nicholas, Vance Jeffery M

Abstract excerpt

Parkinson's disease (PD) has had six genome-wide association studies (GWAS) conducted as well as several gene expression studies. However, only variants in MAPT and SNCA have been consistently replicated. To improve the utility of these approaches, we applied pathway analyses integrating both GWA...

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Source

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Identifiers

PMID: 21364952
DOI: 10.1371/journal.pone.0016917
PMCID: PMC3043094

Genes

MAPT
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21364952-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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