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Article

The role of recombination for the coevolutionary dynamics of HIV and the immune response.

PloS one - 18 Feb 2011

Mostowy Rafal, Kouyos Roger D, Fouchet David, Bonhoeffer Sebastian

Abstract excerpt

The evolutionary implications of recombination in HIV remain not fully understood. A plausible effect could be an enhancement of immune escape from cytotoxic T lymphocytes (CTLs). In order to test this hypothesis, we constructed a population dynamic model of immune escape in HIV and examined the viral-immune dynamics with and without recombination. Our model shows that recombination (i) increases the genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21364750
DOI: 10.1371/journal.pone.0016052
PMCID: PMC3041767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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