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Article

Drosophila happyhour modulates JNK-dependent apoptosis.

Cell death & disease - 19 Aug 2010

Lam D, Shah S, de Castro I P, Loh S H Y, Martins L M

Abstract excerpt

Mitogen-activated protein kinase kinase kinase kinase-3 (MAP4K3) is a Ste20 kinase family member that modulates multiple signal transduction pathways. We recently identified MAP4K3 as proapoptotic kinase using an RNA interference screening approach. In mammalian cells, MAP4K3 enhances the mitocho...

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Identifiers

PMID: 21364671
DOI: 10.1038/cddis.2010.44
PMCID: PMC3032524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21364671-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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