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Article

Histone variant H2A.Z and RNA polymerase II transcription elongation.

Molecular and cellular biology - 1 May 2011

Santisteban Maria Soledad, Hang Mingda, Smith M Mitchell

Abstract excerpt

Nucleosomes containing histone variant H2A.Z (Htz1) serve to poise quiescent genes for activation and transcriptional initiation. However, little is known about their role in transcription elongation. Here we show that dominant mutations in the elongation genes SPT5 and SPT16 suppress the hypersensitivity of htz1Δ strains to drugs that inhibit elongation, indicating that Htz1 functions at the level of...

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Share to Gene Expression Regulation, Fungal
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21357739
DOI: 10.1128/MCB.01346-10
PMCID: PMC3133230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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