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Article

Immunogenetics of pregnancy: role of a 14-bp deletion in the maternal HLA-G gene in primiparous pre-eclamptic Brazilian women.

Human immunology - 1 Aug 2007

Vianna Priscila, Dalmáz Caroline Abrão, Veit Tiago Degani, Tedoldi Citânia, Roisenberg Israel, Chies José Artur Bogo

Abstract excerpt

The etiology and pathogenesis of pre-eclampsia (PE) involve a combination of maternal-fetal genetic and immunologic factors. The immunologic maladaptation theory of PE predicts that the maternal immune system does not tolerate the semi-allogeneic fetus. Human leukocyte antigen-G (HLA-G) is expressed in some types of immune cells as well as in the fetal-maternal interface by trophoblasts, playing an...

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Identifiers

PMID: 17678721
DOI: 10.1016/j.humimm.2007.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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