Article
Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery.
PloS one - 9 Feb 2011
Kiialainen Anna, Karlberg Olof, Ahlford Annika, Sigurdsson Snaevar, Lindblad-Toh Kerstin, Syvänen Ann-Christine
Abstract excerpt
Targeted sequencing is a cost-efficient way to obtain answers to biological questions in many projects, but the choice of the enrichment method to use can be difficult. In this study we compared two hybridization methods for target enrichment for massively parallel sequencing and single nucleotide polymorphism (SNP) discovery, namely Nimblegen sequence capture arrays and the SureSelect liquid-based hybrid capture...
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