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High-performance single-chip exon capture allows accurate whole exome sequencing using the Illumina Genome Analyzer.

Science China. Life sciences - 1 Oct 2011

Jiang Tao, Yang Lei, Jiang Hui, Tian Geng, Zhang Xiuqing

Abstract excerpt

Here we present an adaptation of NimbleGen 2.1M-probe array sequence capture for whole exome sequencing using the Illumina Genome Analyzer (GA) platform. The protocol involves two-stage library construction. The specificity of exome enrichment was approximately 80% with 95.6% even coverage of the...

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PMID: 22038007
DOI: 10.1007/s11427-011-4232-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22038007-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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