Article
Epistatic interaction maps relative to multiple metabolic phenotypes.
PLoS genetics - 10 Feb 2011
Snitkin Evan S, Segrè Daniel
Abstract excerpt
An epistatic interaction between two genes occurs when the phenotypic impact of one gene depends on another gene, often exposing a functional association between them. Due to experimental scalability and to evolutionary significance, abundant work has been focused on studying how epistasis affects cellular growth rate, most notably in yeast. However, epistasis likely influences many different phenotypes,...
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