Article
Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Mar 2002
Featherstone David E, Broadie Kendal
Abstract excerpt
The vast majority (>95%) of single-gene mutations in yeast affect not only the expression of the mutant gene, but also the expression of many other genes. These data suggest the presence of a previously uncharacterized "gene expression network"--a set of interactions between genes which dictate g...
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