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Article

Predictive rule inference for epistatic interaction detection in genome-wide association studies.

Bioinformatics (Oxford, England) - 1 Jan 2010

Wan Xiang, Yang Can, Yang Qiang, Xue Hong, Tang Nelson L S, Yu Weichuan

Abstract excerpt

MOTIVATION: Under the current era of genome-wide association study (GWAS), finding epistatic interactions in the large volume of SNP data is a challenging and unsolved issue. Few of previous studies could handle genome-wide data due to the difficulties in searching the combinatorially explosive search space and statistically evaluating high-order epistatic interactions given the limited number of samples. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19880365
DOI: 10.1093/bioinformatics/btp622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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