Article
Learning genetic epistasis using Bayesian network scoring criteria.
BMC bioinformatics - 31 Mar 2011
Jiang Xia, Neapolitan Richard E, Barmada M Michael, Visweswaran Shyam
Abstract excerpt
BACKGROUND: Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine-learning and data mining methods have been developed for learning epistatic relationships from data. A well-known combinatorial method that has been successfully applied for detecting epistasis is Multifactor Dimensionality Reduction (MDR). Jiang et al. created a combinatorial...
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