Article
A Bayesian method for identifying genetic interactions.
AMIA ... Annual Symposium proceedings. AMIA Symposium - 14 Nov 2009
Visweswaran Shyam, Wong An-Kwok Ian, Barmada M Michael
Abstract excerpt
An important challenge in the analysis of single nucleotide polymorphism (SNP) data is the identification of SNPs that interact in a nonlinear fashion in their association with disease. Such epistatic interactions among genetic variants at multiple loci likely underlie the inheritance of common diseases. We have developed a novel method called the Bayesian combinatorial method (BCM) for detecting combination of...
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