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Article

Identifying genetic interactions in genome-wide data using Bayesian networks.

Genetic epidemiology - 1 Sept 2010

Jiang Xia, Barmada M Michael, Visweswaran Shyam

Abstract excerpt

It is believed that interactions among genes (epistasis) may play an important role in susceptibility to common diseases (Moore and Williams [2002]. Ann Med 34:88-95; Ritchie et al. [2001]. Am J Hum Genet 69:138-147). To study the underlying genetic variants of diseases, genome-wide association studies (GWAS) that simultaneously assay several hundreds of thousands of SNPs are being increasingly used. Often, the...

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PMID: 20568290
DOI: 10.1002/gepi.20514
PMCID: PMC3931553

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GAB2

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