Article
Apolipoprotein E genotypes in primary progressive aphasia.
Neurology - 1 Jul 1997
Mesulam M M, Johnson N, Grujic Z, Weintraub S
Abstract excerpt
We obtained apolipoprotein E genotyping in a population of 12 consecutive patients who fulfilled rigorous criteria for the clinical diagnosis of primary progressive aphasia (PPA). The allele frequencies were 4% for E2, 83% for E3, and 13% for E4. This pattern of allele distribution was significantly different from the pattern seen in groups of patients either with the clinical diagnosis of probable Alzheimer's...
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