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Article

Cognitive phenotypes in Alzheimer's disease and genetic variants in ACE and IDE.

Neurobiology of aging - 1 Jul 2012

Vardy Emma R L C, Brown Kristelle, Stopford Cheryl L, Thompson Jennifer C, Richardson Anna M, Neary David, Kalsheker Noor, Morgan Kevin, Mann David M, Snowden Julie S

Abstract excerpt

Alzheimer's disease (AD) is generally considered to be a disorder primarily affecting memory. It is increasingly recognized that the clinical presentation or "cognitive phenotype" is variable. The apolipoprotein E ε4 (APOE ε4) allele has been associated with an amnestic presentation, but does not appear to fully explain the high prevalence of family history within this group. We examined polymorphisms in the...

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Source

Identifiers

PMID: 21232820
DOI: 10.1016/j.neurobiolaging.2010.11.003

Genes

ACE
IDE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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