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Article

Direct Evidence for Multiple Self-Renewal Divisions of Human In Vivo Repopulating Hematopoietic Cells in Short-Term Culture

1 Oct 1999

Abstract excerpt

Recently, culture conditions that stimulate the proliferation of primitive hematopoietic cells defined by various phenotypic and functional endpoints in vitro have been identified. However, evidence that they support a high probability of self-renewal leading to a large net expansion in vitro of transplantable cells with lympho-myeloid repopulating ability has been more difficult to obtain. The present study was...

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Identifiers

PMID: 10498585
DOI: 10.1182/blood.v94.7.2161.419k32_2161_2168

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Source receipt: pubmed, retrieved 7 Sept 2026.

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