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Article

DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression

21 Feb 2011

Abstract excerpt

We explored the associations of aberrant DNA methylation patterns in 12 candidate genes with adult glioma subtype, patient survival, and gene expression of enhancer of zeste human homolog 2 (EZH2) and insulin-like growth factor-binding protein 2 (IGFBP2). We analyzed 154 primary glioma tumors (37 astrocytoma II and III, 52 primary glioblastoma multiforme (GBM), 11 secondary GBM, 54...

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PMID: 21339190
DOI: 10.1093/neuonc/noq190

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