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Article

ZEB1 expression is increased in IDH1-mutant lower-grade gliomas.

Journal of neuro-oncology - 1 Oct 2016

Nesvick Cody L, Zhang Chao, Edwards Nancy A, Montgomery Blake K, Lee Michaela, Yang Chunzhang, Wang Herui, Zhu Dongwang, Heiss John D, Merrill Marsha J, Ray-Chaudhury Abhik, Zhuang Zhengping

Abstract excerpt

Transcription factors that induce epithelial-mesenchymal transition (EMT) promote invasion, chemoresistance and a stem-cell phenotype in epithelial tumors, but their roles in central nervous system tumors are not well-understood. We hypothesized these transcription factors have a functional impact in grades II-III gliomas. Using the National Cancer Institute (NCI) Repository for Molecular Brain Neoplasia Data...

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Source

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Identifiers

PMID: 27568035
DOI: 10.1007/s11060-016-2240-8
PMCID: PMC6088798

Genes

ZEB1
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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