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Article

RIT2 polymorphism is associated with Parkinson's disease in a Han Chinese population.

Neurobiology of aging - 1 Mar 2015

Nie Kun, Feng Shu-jun, Tang Hong-mei, Ma Gui-xian, Gan Rong, Zhao Xin, Zhao Jie-hao, Wang Li-min, Huang Zhi-heng, Huang Jing, Gao Liang, Zhang You-wen, Zhu Rui-ming, Duan Zhen-peng, Zhang Yu-hu, Wang Li-juan

Abstract excerpt

Recently, a meta-analysis including 5 large genome-wide association studies has identified rs12456492 variant of RIT2 gene as a novel risk locus for Parkinson's disease (PD) in Caucasian populations. However, the association between RIT2 polymorphism and PD risk has not been positively replicated in Asian population yet. We detected the genotypes of rs12456492 in 524 PD patients and 521 control subjects from a...

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Source

Identifiers

PMID: 25457028
DOI: 10.1016/j.neurobiolaging.2014.10.013

Genes

RIT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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